01Mast cell tumourA skin mass with mast cells identified on FNA
RECORD BEFORE REFERRAL

Clinical risk factors

These findings may change the surgical plan and estimate.

  • Maximum diameter and exact location
  • Growth rate, ulceration, recurrence or regrowth
  • Previous surgery or biopsy and the scar location
  • Systemic signs and regional lymph-node findings
FNA Usually diagnostic. It does not provide a histologic grade. Handle gently Avoid repeated squeezing, especially when the mass is painful, fragile, ulcerated, or reactive.
Veterinary illustration of a dog with a cutaneous mast cell tumour and an inset showing mast cells on cytology
FNA is usually diagnostic for mast cell tumour, but histology is required for grade and margin assessment.
WHAT MAY HAPPEN AFTER REFERRAL

Sentinel-node mapping and risk-directed staging may change the operation

RISK-DIRECTED STAGING

When to add abdominal or local staging

For uncomplicated cutaneous mast cell tumours, the routine staging priority is not the chest. Additional staging is selected when it could change the surgical plan.

Review the features that may change staging
  • Large, fixed, ulcerated, rapidly growing, or recurrent masses
  • Multiple mast cell tumours with systemic illness, an abnormal CBC, or a biopsy already showing high-grade disease
  • Facial or muzzle, oral or perioral, preputial, or perineal location

Further staging may include abdominal ultrasound with targeted liver and spleen samples, local imaging for a deep or complex mass, or a preoperative biopsy when grade could change the surgical plan.

WHY SENTINEL MAPPING MATTERS

40%-63% may drain somewhere unexpected

Across published canine mast cell tumour studies, the mapped sentinel lymph node differed from the expected anatomical node in 40% to 63% of cases. This is why the mapped draining node, rather than only the nearest node, is important to surgical staging.

Labelled canine regional lymph-node map
Regional lymph-node map
Close view of a thigh mass tracing to a popliteal sentinel lymph node
Sentinel mapping can identify a different draining node.
57% differed in a 138-tumour mapping study 60% had nodal metastasis in one fully staged referral cohort

138-case mapping study · sentinel-node staging study

PUBLISHED SURGICAL PRICES

The closure and lymph-node field set the range

Mass plus same-field lymph node
$4,500-6,000
Flap or graft reconstruction
$5,800-8,000
Separate-field lymph node
$7,800-10,500

Pre-tax. Histopathology and routine rechecks for 12 months are included in these oncology tiers. Review the full price guide.

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02Soft-tissue sarcomaA firm or deep mass with spindle or mesenchymal cells, or a nondiagnostic FNA that remains concerning
RECORD BEFORE REFERRAL

Clinical risk factors

These findings may change the surgical plan and estimate.

  • Maximum diameter in three dimensions, including whether it is over 5 cm
  • Whether the mass is superficial or deep to the fascia, and mobile or fixed
  • Whether it is recurrent or was previously removed without planned margins
  • Any previous histopathology, including the reported grade, and the scar or biopsy-tract location
FNA May identify or suggest spindle or mesenchymal cells, but is sometimes nondiagnostic. If the interpretation is uncertain, submit the sample to a clinical pathologist. Chest imaging 3-view radiographs provide a preoperative baseline.
Veterinary illustration of a dog with a deep soft-tissue mass and an inset showing a low-cellularity spindle-cell cytology pattern
A low-cellularity or nondiagnostic FNA is not automatically reassuring.
WHAT MAY HAPPEN AFTER REFERRAL

CT and biopsy are selected only when they could change the margins or closure plan

When contrast CT may be recommended

Contrast-enhanced CT is Dr. Wood's usual additional local planning test when a mass is over 5 cm, deep, fixed, poorly defined, recurrent, close to a joint or an important nerve or blood vessel, or when wide margins in that location may require a flap, graft, or other closure plan.

CT shows the relationship between the mass and the tissues that may need to be removed or reconstructed. It does not provide a tumour grade.

When a preoperative biopsy may be recommended

A deliberately placed core or incisional biopsy may be useful for a distal-limb or other constrained mass when the result could change the margins, reconstruction, or whether to proceed with an operation that has substantial functional impact. The biopsy tract must be positioned so it can be removed with the definitive surgery.

Biopsy grade is not definitive. In a study of 68 dogs, the preoperative biopsy grade matched the complete-excision grade in 59% of soft-tissue sarcomas. It underestimated the final grade in 29% and overestimated it in 12%.

68-dog biopsy-grade study · spindle-cell sarcoma cytology study

PUBLISHED SURGICAL PRICES

The closure plan is the main price distinction

Primary closure
$3,000-4,700
Flap or graft reconstruction
$5,800-8,000

Pre-tax. Histopathology and routine rechecks for 12 months are included. Imaging or biopsy performed before definitive surgery is estimated separately. Review the full price guide.

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03LipomaAdipose tissue on FNA with a compatible superficial mass
RECORD BEFORE REFERRAL

Features that change planning

These findings help distinguish a simple superficial mass from one that needs CT planning.

  • Maximum diameter, exact location, and whether the mass is superficial or deep
  • Whether it is freely mobile, fixed, poorly defined, or within a muscle
  • Any pain, altered movement, weakness, or other signs that may indicate nerve involvement
  • Previous surgery and whether the mass has recurred
FNA Adipose tissue supports a simple lipoma only when the sample and examination agree.
Veterinary illustration of a dog with a superficial mobile mass and an inset showing mature adipose tissue on cytology
Adipose tissue supports a simple lipoma only when the FNA and examination agree.
WHAT MAY HAPPEN AFTER REFERRAL

CT may be recommended for a deep or anatomically complex lipoma

Why CT and 3D planning may be useful

For a large, deep, intramuscular, recurrent, fixed, or anatomically complex lipoma, CT can map the muscle compartments, vessels, and the expected or visible course of important nerves. Dr. Wood reviews the CT and performs his own 3D reconstruction for surgical planning.

CT can also suggest an infiltrative pattern. In a study of 60 adipose masses, 75% of infiltrative lipomas were irregular and 100% contained linear soft-tissue components. Histopathology provides the final diagnosis.

60-lesion CT comparison study · 11-dog intermuscular lipoma study

PUBLISHED SURGICAL PRICE

Simple mass removal

Simple mass removal
$3,000-4,700

Pre-tax. Histopathology and routine rechecks for 12 months are included. CT, when recommended, is planned separately. Review the full price guide.

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04Mammary massOne or more mammary lesions in a cat or dog
RECORD BEFORE REFERRAL

Clinical risk factors

These findings may change the surgical plan and estimate.

  • Affected gland and maximum diameter of every mass
  • Growth rate, fixation, ulceration, discharge, or pain
  • Axillary and superficial inguinal lymph-node findings
  • Previous surgery or biopsy and the scar location
Chest imaging 3-view radiographs are recommended before surgery. Regional lymph node Assess and sample the relevant node during the same procedure when indicated.
WHAT MAY HAPPEN AFTER REFERRAL

Species, distribution, staging, and closure needs determine the operation

SURGICAL PLANNING

Species and tumour distribution change the operation

Cats

Feline mammary tumours are more often malignant. When both chains require surgery, Dr. Wood typically recommends staged bilateral mammary-chain surgery. The timing is planned from disease distribution, patient health, and closure requirements.

Dogs

The number, size, location, fixation, and lymphatic field determine whether a limited removal, regional procedure, or chain procedure is discussed.

Routine abdominal imaging is not usually required. The relevant regional lymph node can be assessed and sampled during the mammary procedure when indicated.

WHY SIZE IS RECORDED

3 cm changes the prognosis discussion

Maximum tumour diameter is one of the simplest useful risk features to record before referral. It does not replace histology, but it helps frame staging and surgical urgency.

Dogs commonly grouped as under 3 cm, 3-5 cm, and over 5 cmCats tumours over 3 cm have a poorer prognosis in published series

canine mammary tumour size study · feline mammary carcinoma study

PUBLISHED SURGICAL PRICES

Limited, unilateral, staged, and single-session bilateral surgery

Limited removal with primary closure
$3,000-4,700
Feline unilateral mammary chain
$4,500-6,000
Staged second feline chain
$3,000-4,700
Feline bilateral chains, single session
$7,800-10,500

Pre-tax. Histopathology and routine rechecks for 12 months are included. The examination determines whether limited removal, a unilateral procedure, staged treatment, or selected single-session bilateral surgery is appropriate. Review the full price guide.

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05Digit or nail-bed lesionPersistent nail loss, swelling, ulceration, pain, or bone lysis
RECORD BEFORE REFERRAL

Clinical risk factors

These findings may change the surgical plan and estimate.

  • Exact digit and maximum lesion diameter
  • Nail loss or deviation, ulceration, discharge, or bleeding
  • Duration, growth, pain, lameness, and response to treatment
  • Previous surgery or biopsy and regional lymph-node findings
Radiographs Sedated orthogonal views of the affected digit and foot. FNA or biopsy Select according to the lesion, with histology after amputation. Chest imaging 3-view radiographs are recommended when malignancy is suspected.
WHAT MAY HAPPEN AFTER REFERRAL

Imaging, tissue diagnosis, node assessment, and amputation planning are considered together

SURGICAL PLANNING

Match the operation to the species and imaging

Dogs

Persistent nail-bed lesions, especially with bone lysis, require a tumour work-up even when infection is also present. Radiographs and tissue diagnosis guide biopsy, digit amputation, and regional-node assessment.

Cats

A destructive digital lesion may be a primary tumour or metastatic disease. Thoracic imaging is particularly important because lung tumours can spread to the digits.

WHY BONE LYSIS MATTERS

83% were malignant

In a 117-case study of canine digit masses with bone lysis, 83% were malignant. Infection can still coexist, so drainage or inflammation should not end the tumour work-up.

Bone lysis raises concern for malignancyTissue diagnosis is still required

117-case canine digit study

PUBLISHED SURGICAL PRICES

Digit amputation is usually a primary-closure procedure

Digit amputation
$3,000-4,700
With same-field lymph node
$4,500-6,000

Pre-tax. Histopathology and routine rechecks for 12 months are included. Staging and any preoperative biopsy or advanced imaging are planned separately. Review the full price guide.

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06Anal sac mass / suspected AGASACAAnal sac apocrine gland adenocarcinoma or another anal sac lesion
RECORD BEFORE REFERRAL

Clinical risk factors

These findings may change the surgical plan and estimate.

  • Affected side and maximum diameter, including whether it is over 2.5 cm
  • Findings in the opposite anal sac and on rectal examination
  • Tenesmus, constipation, stool change, thirst, urination, weakness, or appetite change
  • Previous surgery or biopsy and available calcium results
Rectal exam and FNA Assess both anal sacs and sample the mass when accessible. Bloodwork CBC, chemistry, total calcium, and ionized calcium when indicated. Further staging Consider contrast CT of the abdomen and pelvis when the primary is over 2.5 cm, nodes are enlarged or abnormal, there are obstructive or systemic signs, calcium is increased, or surgery is being planned.
WHAT MAY HAPPEN AFTER REFERRAL

CT, regional-node surgery, and bilateral anal-sac removal may be discussed

STAGING AND SURGICAL PLANNING

Use size as a risk marker, not a rule that replaces staging

The historical clinical scheme separates primary tumours at 2.5 cm. However, a small primary mass or normal calcium does not rule out regional nodal disease.

How CT findings are interpreted
  • In one series, 20% of dogs with a primary mass under 2 cm already had confirmed lymph-node metastasis.
  • One bilateral-surgery study treated a regional node over 5 mm, or abnormal in shape or internal appearance, as suspicious. Size alone does not confirm metastasis.
  • Cytology or histopathology is used to establish nodal metastasis. Once nodal disease is confirmed, the published clinical scheme separates nodal stages at 4.5 cm.
  • CT also shows the relationship to the rectum, pelvic canal, vessels, and ureters when surgery is planned.

small-primary metastasis study · bilateral anal-sac study and staging scheme

WHY CT AND BILATERAL DISCUSSION MATTER

20% had hidden bilateral disease

A 2024 study found cancer in both anal sacs in 7 of 35 dogs whose preoperative work-up suggested disease on only one side. This supports discussing bilateral removal, while the final recommendation remains patient specific.

61 nodes identified with CT in one comparison30 nodes identified with ultrasound

bilateral anal-sac study · CT versus ultrasound study · CT staging study

PUBLISHED SURGICAL PRICE

Bilateral anal-sac removal

Bilateral anal sacs
$5,800-8,000

Pre-tax. Histopathology and routine rechecks for 12 months are included. Advanced imaging or a separate lymph-node operation is planned and estimated individually. Review the full price guide.

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07Perineal massPerianal or perineal skin and gland presentation
RECORD BEFORE REFERRAL

Clinical risk factors

These findings may change the surgical plan and estimate.

  • Maximum diameter, including whether it is over 5 cm
  • Fixation or deep invasion, ulceration, recurrence, or rapid growth
  • Rectal examination, both anal sacs, and regional lymph-node findings
  • Previous surgery or biopsy and the scar location
FNA and rectal exam Define the tissue of origin and assess both anal sacs. Neuter status For some perianal-gland masses in intact male dogs, neutering may be recommended with mass removal.
WHAT MAY HAPPEN AFTER REFERRAL

Most superficial masses proceed to a simple-removal discussion

ANATOMY-DIRECTED PLANNING

CT or biopsy is selective, not routine

A small, superficial perianal-gland mass in a typical patient may need only FNA, rectal examination, and a simple-removal plan.

When CT or biopsy may be added

They may be recommended when a suspected perianal or hepatoid-gland tumour is over 5 cm, fixed or invasive, recurrent, of uncertain tissue origin, or when the result could change the margins or closure plan. The 5 cm finding does not apply to anal-sac cancer.

WHY SIZE AND ORIGIN MATTER

5 cm changes the risk discussion

For perianal or hepatoid-gland adenocarcinoma, published data associate tumours over 5 cm with a substantially higher risk of tumour-related death. Regional lymph-node spread has been reported in about 15% of dogs.

Over 5 cm about 11 times higher tumour-related death riskAbout 15% regional lymph-node metastasis

This evidence does not apply to anal-sac apocrine gland adenocarcinoma, which has a separate pathway above. Review the hepatoid-gland tumour evidence.

PUBLISHED SURGICAL PRICES

Most superficial perineal masses use the simple-removal tier

Simple mass removal
$3,000-4,700
Flap or larger reconstruction, if required
$5,800-8,000

Pre-tax. Histopathology and routine rechecks for 12 months are included. Neutering can be added to the surgical plan and estimate when recommended. A rectal, anal-sac, deep pelvic, or separate lymph-node procedure is estimated according to the operative fields involved. Review the full price guide.

Start referral
Written and medically reviewed by Chris Wood, BSc, DVM (Dist), MS, DACVS-SA Last reviewed: August 30, 2026 General education for veterinary teams; case-specific assessment takes priority. Review policy